Once again for those of you who are just joining us, Day Of Transplant = DOT
Dot- 4 means 4 days to go.
Houston, do we have ignition?
A brief excursion to the brink, and how to know where the brink is.
Ready ? 1.2.3. jump
Soundtrack
Gimme that Wine ( Unhand that Bottle )
Lambert , Hendricks and Ross, 1962
pharmacodynamic tolerance
My Dacogen dose at the Raab clinic was determined by a height/weight body mass formula, and that is how this initial dose of this chemo was set.
It is like knowing your limits, and one more beer isn't going to make you feel any better, despite the urgings of your limbic system.
The other obvious factors that determine the brink are blood levels, electrolytes, digestion and elimination ok,, mouth sores, infections fungal and bacterial, and general state of malaise.
The other obvious factors that determine the brink are blood levels, electrolytes, digestion and elimination ok,, mouth sores, infections fungal and bacterial, and general state of malaise.
Myelotoxicity
Myelotoxicity is the most common complication of cancer chemotherapy.
It can damage the bone marrow.
Well how about that. Just what we need to nail those pesky mutant cells that are cranking out defective products. The goal is to wipe out my the stem cells in my Marrow.
Bring it on! Chemo is my friend.
I can ride it out.
It can damage the bone marrow.
Well how about that. Just what we need to nail those pesky mutant cells that are cranking out defective products. The goal is to wipe out my the stem cells in my Marrow.
Bring it on! Chemo is my friend.
I can ride it out.
Most Cases of MDS are not de novo like mine , but arise from chemo treatment for other cancers. See my post of what causes MDS , and my rant on socio-environmentally induced low dose de novo here.
For the Geeks:
References:
The Oncologist Magazine has a
Except that maybe a HEPA filter in the infusion room would help
1994 by American Society of Clinical Oncology
More out there, but this is pushing the limits of my role as an Amateur Hematologist.
Chris Siegel, B.S. , A.H. USCG Capt. License Holder, lapsed
Oh, there was this interesting bit from the interwebs.
Mithridatism is the practice of protecting oneself against a poison by gradually self-administering non-lethal amounts. The word derives from Mithridates VI, the King of Pontus, who so feared being poisoned that he regularly ingested small doses, aiming to develop immunity.
Like I was unknowingly doing with boatyard toxins. It doesn't work. WEAR YOUR MASK AND GLOVES!
More tomorrow,
Chris
Like I was unknowingly doing with boatyard toxins. It doesn't work. WEAR YOUR MASK AND GLOVES!
More tomorrow,
Chris
Smooth sailing and Godspeed! Evie
ReplyDeleteI picked up on some of this info back when Wally Gator was fighting the good fight but, as always, your sense of humor makes the read not only enlightening but enjoyable. Thanks, Chris! Fare Thee Well!
ReplyDeleteramona and i laughed through this post. we moved the bed today and now she is worried she will walk into the wall in the middle of the night. hilarity! salut! prost!
ReplyDeleteJ + R,
DeleteAnne and I switched bed sides last night so I would have a straight shot to the head. Walked into the wall.
Do do do do do do do do Twilight Zone.
Needs to be Nightlight Zone.
Aye,
And the toast I would have given at your wedding , to the chagrin of many I fear.
"She Offered her Honor
He Honored her Offer
and it was on her and off her all night long!"
good god that's amazing and hilarious and... yup, night lights.
Deletethanks for all the great music clips. but the BS&T song, gotta say, don't believe I've ever seen the title written. I just sing it... in the present.
ReplyDeleteso, to you Chris, Confucius say "very happy, very happy, you make miso. very happy."
Miso Happy? Is this from a Wahine or a Tahini?
ReplyDelete